Spin trapping of active oxygen radicals for medical and biological scientists.
نویسندگان
چکیده
منابع مشابه
synthesis and characterization of potentially biological active cyclometallated organoplatinum(ii) complexes
this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...
15 صفحه اولSpin Trapping Technique Studies on Active Oxygen Radicals from Human Polymorphonuclear Leukocytes during Fluoride-stimulated Respiratory Burst
By means of the ESR spectrum technique it was demonstrated that fluoride (F-) stimulated human polymorphonuclear leukocytes (PMN) in a respiratory burst to generate active oxygen radicals ( • 02 and -OH) and to consume oxygen (02). The experiments' using the spin trapping technique with the nitrone DMPO as the trapping agent indicated that the PMN produce the adduct DMPO-OOH under high concentr...
متن کاملSignal enhancement in ESR spin-trapping for hydroxyl radicals.
In an ESR spin-trapping measurement of hydroxyl radicals formed in a Fenton reaction, the trapping efficiency with DMPO increased by about 300 times in a sodium trifluoroacetate solution, whereas it was little changed in a phosphate buffer.
متن کاملLipid radicals: properties and detection by spin trapping.
Unsaturated lipids are rapidly oxidized to toxic products such as lipid hydroperoxides, especially when transition metals such as iron or copper are present. In a Fenton-type reaction Fe2+ converts lipid hydroperoxides to the very short-lived lipid alkoxyl radicals. The reaction was started upon the addition of Fe2+ to an aqueous linoleic acid hydroperoxide (LOOH) emulsion and the spin trap in ...
متن کاملSpin Trapping of Radicals in Gas-Phase Cigarette Smoke
Since the spin trapping technique was developed and utilized to determine radicals in the gas phase (see reviews [1—3]), it has become attractive as a method of detecting radicals in gas-phase tobacco smoke. A first study of this sort was reported by Bluhm et al. in 1971 [4], while previous studies were forced to rely on the measurements of smoke condensate at liquid nitrogen temperature [5, 6]...
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ژورنال
عنوان ژورنال: Ensho
سال: 1985
ISSN: 0389-4290,1884-4006
DOI: 10.2492/jsir1981.5.3